Thymosin beta-4, also commonly known as TB-500, is a 43 amino acid protein encoded by the TMSB4X gene in humans. Thymosin beta-4 is a manufactured form of a peptide that is present in all animal and human cells and is is part of a group of 16 associated molecules. Thymosin beta-4 is a potent peptide that is typically present in wound fluid, thus the potential benefits for wound healing, building of muscle mass, and fiber/cell recovery time is great. Thymosin beta-4 binds with actin in the cytoskeleton, blocks actin polymerization, assists cell migration, and accelerates production of extracellular matrix-degrading enzymes.
Thymosin beta-4 may differ from other repair factors, such as IGF-1 for example, in how it appears to promote endothelial and keratinocyte migration. And as thymosin beta-4 has a low molecular weight, it is able to easily travel further distances through tissues.
Thymosin beta-4 is often delivered as a lyophilized powder (2.0mg vials) designed for subcutaneous injection. Reconstitute with sterile saline or sterile bacteriostatic water. Doctors will make specific dosing recommendations for individual patients based on factors such as the patient's medications, conditions, height, weight, age, and gender. For questions, consult product-packaging directions, consult the manufacturer, or ask your compounding pharmacist.
"It is rare to find health professionals who are so willing to educate the patient on what they need to know."