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Sertraline is a custom pharmacy drug that is classified in the group of drugs known as selective serotonin reuptake inhibitors (SSRIs). Sertraline works within the brain to increase serotonin, which may, in some patients, help to achieve mental balance. Sertraline is often prescribed for the ongoing treatment of anxiety, panic disorder, depression, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), and obsessive-compulsive disorder (OCD).


Sertraline is typically taken orally, administered as a liquid or tablet. Standard dosage is once per day, but your physician will decide exactly what your dosage should be. Follow your physician's directions exactly. If your physician prescribes liquid (concentrate) you must dilute your dose in a glass of water or juice (typically 4 ounces) before ingesting. Be sure to use only the approved dropper to measure your dose. Never use a teaspoon, other measuring device, or utensil as this will invariably give you an inaccurate dose of the medication.

Consult with your compounding pharmacist if you have any questions about sertraline regarding its usage or efficacy.


Pharmaceutical drugs can offer wonderful benefits in regard to prevention and treatment, but unfortunately for some patients and users, side effects may also be a possible outcome. Side effects may differ from person to person and until one begins taking a new drug or medication they will not know exactly how it will affect them. Therefore if you are prescribed sertraline it is important to have a comprehensive discussion with your physician about all possible side effects so you will be armed with the knowledge you need if you do experience any. Common side effects seen with sertraline are:

  • Trouble Falling Asleep
  • Difficulty Staying Asleep
  • Change In Sex Drive
  • Change In Sexual Ability
  • Xerostomia
  • Weight Changes
  • Heartburn
  • Loss Of Appetite
  • Nausea
  • Diarrhea
  • Constipation
  • Vomiting
  • Nervousness
  • Excessive Tiredness
  • Excessive Sweating
  • Dizziness
  • Headache
  • Uncontrollable Shaking

Other side effects are possible. If any side effects increase in intensity or linger, see your physician.

Severe Side Effects:

Some users may experience more severe side effects. If you experience anything that feels severe, see your physician immediately, or get prompt medical attention at a healthcare facility. Some of the more commonly seen potentially severe side effects are listed below. Please note this list is not comprehensive and you may experience a severe side effect not listed herein.

  • Difficulty Breathing
  • Seizures
  • Nausea
  • Vomiting
  • Diarrhea
  • Abnormal Bleeding
  • Abnormal Bruising
  • Agitation
  • Hallucinations
  • Confusion
  • Fever
  • Shivering
  • Sweating
  • Accelerated Heartbeat
  • Severe Muscle Stiffness
  • Rash
  • Hives
  • Swelling
  • Severe Twitching
  • Loss of Coordination

WARNING: Some users (up to 24 years of age) who took sertraline in clinical studies developed suicidal thoughts. If you experience any suicidal thoughts whatsoever, see your physician immediately or get medical help at once.


If you are considering the use of sertraline, talk to your physician to discuss all your options for treatment. Never take sertraline or any new drug or medication without the expressed approval from your physician.

Sertraline is contraindicated for all of the following:

  • Disulfiram Use
  • Hypersensitivity to Sertraline or itsIngredients

WARNING: It may be harmful to abruptly withdraw from the use of sertraline. Talk to your physician about the risks.

Sertraline may be contraindicated, in some cases, for any of the following:

  • Alcohol Use
  • History of Seizure
  • Volume Depletion
  • In Elderly Patients
  • Pregnancy (3rd trimester)
  • Bleeding Risk
  • Hepatic Impairment
  • History of Mania
  • History of Hypomania
  • Glaucoma
  • Concurrent CNS Depressant Use
  • In Patients Less Than 25 Years of Age
  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA