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Pyridoxine (vitamin B6)

Pyridoxine (vitamin B6) is an important B vitamin that we sometimes receive into our bodies through the consumption of healthy foods such as fish, poultry, bananas, potatoes, chickpeas, spinach, milk, cheese, beans, brown rice, bran and more. However, some people may not get enough of this important vitamin naturally through their diet, for these people a pyridoxine supplement may be beneficial. The overall importance of this essential vitamin is immense as it helps to maintain and control the functioning of nerves, helps to produce red blood cells, and assists with the metabolization of proteins and fats. A pyridoxine/vitamin B6 deficiency may cause serious problems such as low red blood cell count, which can lead to a weakened immune system. Some possible signs of a deficiency may be irritability or nervousness, difficulty concentrating, possible short-term memory loss, and weakness. See your doctor if you experience any of the aforementioned. Some of the many potential benefits of pyridoxine (vitamin B6) that are under current study are as follows:

  • Lowered Risk of Heart Disease
  • Prevention of Kidney Stones
  • Prevention of Various Types of Macular Degeneration
  • Improvement of Premenstrual Syndrome Symptoms
  • Treatment of Carpal Tunnel Symptoms
  • Treatment of Nausea and Vomiting (during pregnancy)
  • Treatment of Anemia (certain type)
  • Prevention of Certain Types of Cancer
  • Treatment of Acne
  • Treatment of Seizures in Infants
  • Treatment of Select Skin Conditions
  • Improvement of Cognitive Function in Older Adults
  • Improvement of Memory
  • Treatment of Rheumatoid Arthritis
  • Improvement of Symptoms related to Tardive Dyskinesia
  • Possible Improvement of Behavioral Disorders (in children)


Pyridoxine should be taken orally once a day or as directed by your doctor. A few of the various forms it may come in are tablets, capsules, and powders. It can be taken with food, or without. Never chew or crush extended-release tablets or capsules. Your doctor will decide your dosage; follow his or her directions.


Many types of side effects are possible while taking pyridoxine. Some patients taking pyridoxine may not experience or encounter any side effects at all, others may be less fortunate and experience one or more side effects. Some side effects may commence at the beginning of a patient's course of pyridoxine then dissipate. Other side effects may commence then linger, or perhaps increase in intensity. If you experience any side effect that seems to be lingering or increasing in intensity, see your doctor. Common side effects seen with pyridoxine are:

  • Sensitivity to Sunlight
  • Sleepiness
  • Upset Stomach
  • No Appetite
  • Tingling, Prickling, or Burning Sensation (hands, feet)
  • Headache

It is important to note that your individual experience may be different than the average patient/user and as such you might experience side effects not listed or perhaps not seen in the average patient/user taking this drug. Watch for potential side effects and remember to see your doctor if any linger or seem to be increasing in intensity.

Severe Side Effects:

While many users do not experience severe side effects while taking pyridoxine, nevertheless, severe side effects are a possibility with any drug, medication, vitamin, or supplement, especially in higher concentrations or doses. With this in mind, it is important to note that pyridoxine can, in high doses, lead to potential neurological disorders that may bring about a loss of feelings in the legs or possibly some balance problems. In most people, simply lowering the amount or dose will resolve these issues, but it is best to see your doctor right away if you experience any of the aforementioned.


If you are interested in learning more about pyridoxine and think that it might be appropriate for treating your medical condition or improving your health, set an appointment with your doctor and undergo a comprehensive medical screening. Never begin taking pyridoxine or any new drug without seeing your doctor for a screening and receiving her or his approval for use.

Pyridoxine may, in some cases, be contraindicated depending on the health status of a patient, age, medical conditions, diseases, or drug interaction issues. Discuss all possible contraindications with your doctor. Only your doctor can decide if pyridoxine will be safe for you to take.

In most people, pyridoxine is tolerated well.

Pyridoxine is contraindicated for anyone with a hypersensitivity to pyridoxine, its drug class, or ingredients.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA