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Primidone is a custom pharmacy drug classified in the family of drugs known as anticonvulsants. Primidone is primarily used as a medication to control seizures. It is sometimes prescribed for treatment as a standalone medication or in concert with other medications. In some people, abnormal electrical signals may be released within the brain, which can cause the brain to be over-stimulated. This may lead to seizures. Primidone helps to control seizures by decreasing the abnormal electrical activity within the brain.


Primidone is typically taken orally, three to four times a day as prescribed by your physician. It should be taken on a regular schedule for best results, so make an effort to take it at the same time of day on your dosage days. In some patients, physicians may opt to prescribe a very low dose as the body adjusts slowly and then prescribe an increase of that dose over time. Never increase or decrease your dosage unless your physician orders a change in dosage. Consult with your compounding pharmacist if you have general questions about drug potency or properties. Always follow your physician's directions regarding dosage and usage of any drug you are taking.


Side effects may vary between patients due to a wide assortment of reasons. Some patients may experience few side effects, or perhaps none at all. Others may experience several side effects. Until you begin taking primidone it is not possible to predict how it will affect you, so talk to your physician about possible side effects and be prepared if you experience any. Common side effects seen with primidone are:

  • Dizziness
  • Excessive Tiredness
  • Difficulty with Coordinating Movements / Coordination
  • Decrease in Sexual Ability
  • No Appetite
  • Nausea and/or Vomiting
  • Double Vision
  • Uncontrolled Eye Movements

NOTE: If you experience any side effects that are worsening or persisting/lingering, see your physician.

Severe Side Effects:

While it is possible that you may experience no severe side effects while taking primidone, severe side effects are certainly a real possibility for anyone. There may be many kinds and types of severe side effects, known and unknown. Ask your physician to discuss all possible side effects, severe and common. If you experience anything at all that feels severe, seek emergency medical treatment at once.


Primidone is a powerful drug and as such should not be taken or used by anyone without the prior approval from their primary care physician who has comprehensive and intimate knowledge of their medical and drug histories.

Primidone is contraindicated for the following:

  • Porphyria
  • Hypersensitivity to Phenobarbital

There may be many more possible contraindications for primidone. Ask your physician to discuss all possible contraindications during your initial consultation. Never take primidone if it is contraindicated for your use or inadvisable due to your age, health status, or otherwise. Only your physician can decide if primidone is safe for you.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA