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Paroxetine is a custom pharmacy drug classified in the family of drugs known as selective serotonin reuptake inhibitors (SSRIs). Paroxetine works within the brain to perform the task of balancing select chemicals, which may possibly improve various mental health conditions. Paroxetine is often given for the treatment of anxiety, obsessive-compulsive disorder (OCD), depression, and post-traumatic stress disorder (PTSD). Sometimes paroxetine is prescribed for premenstrual dysphoric disorder (PMDD) as well, and certain brands of paroxetine may be used to treat symptoms resulting from menopause, such as hot flashes.


As is true with many drugs, paroxetine can be compounded into various forms of delivery by special request (based on your doctor's recommendations). Typically, this drug is administered via tablets, long-acting tablets, suspensions, and capsules, each with its own particular set of directions for usage and dosage. Ask your doctor to explain how to take this drug and follow his or her directions exactly regarding usage and dosage. Consult with your compounding pharmacist if you have more questions regarding general use when you pick up your prescription.


Side effects are always a possibility whenever you introduce any drug into your body. Some side effects may pass quickly after your body becomes used to the drug, but others may linger. If you experience any side effects whatsoever that linger or get worse, see your doctor. Common side effects seen with paroxetine are:

  • Nausea
  • Vomiting
  • Constipation
  • Gas
  • Stomach Pain
  • Diarrhea
  • Painful Menstruation
  • Abnormal Menstruation
  • Change in Tasting of Food
  • Decreased Appetite
  • Weight Loss
  • Weight Gain
  • Heartburn
  • Change in Libido
  • Change in Sexual Function
  • Yawning
  • Xerostomia
  • Sweating
  • General Body Pain
  • Muscle Pain
  • Back Pain
  • Bone Pain
  • Swelling Joints
  • Noticeable Muscle Weakness
  • Lump in Throat
  • Flushing
  • Headache
  • Dizziness
  • Weakness
  • Nervousness
  • Difficulty Concentrating
  • Confusion
  • Forgetfulness
  • Sleepiness
  • Sore Gums and/or Teeth
  • Odd or Abnormal Dreams
  • Light Sensitivity

Severe Side Effects:

Some patients may experience certain side effects that could be classified as severe. If you experience any severe side effects while taking this drug, see your doctor at once or get immediate emergency medical treatment. A partial list of severe side effects is provided below:

  • Chest Pain
  • Difficulty Breathing
  • Sweating
  • Swelling (possibly anywhere in the body)
  • Uncontrollable Shaking
  • Black and/or Tarry Stools
  • Red Blood in Stools
  • Seizures
  • Hallucinations
  • Fainting
  • Sudden Nausea
  • Vomiting
  • Dizziness
  • Bone Pain
  • Severe Muscle Stiffness
  • Twitching
  • Abnormal Bleeding
  • Numbness and/or Tingling (hands, feet, arms, legs)
  • Bruising
  • Red Spots Under Skin
  • Blistering
  • Peeling
  • Painful Erection that Endures
  • Headache
  • Confusion or Feeling Disoriented
  • Hives and/or Skin Rash
  • Painful Urination
  • Other General Urination Problems
  • Rapid Heartbeat
  • Irregular Heartbeat
  • Vomit with Blood
  • Vomit (that appears like coffee grounds)
  • Sore Throat and/or Cough
  • Signs of Infection
  • Unsteady Gait
  • Infection in Vagina (possibly with pain, burning, itching, etc.)
  • Hoarseness
  • Fever
  • Itching


    Paroxetine may be contraindicated for various diseases, medical conditions, possible drug interactions, or for specific reasons related to your health status or age, etc. It is important to discuss all possible contraindications with your doctor before beginning use of paroxetine. Only your doctor can decide if this drug is safe for your use and necessary for your treatment.

    Paroxetine is contraindicated for the following:

    • Anyone Under the Age of 18 Years
    • Anyone Experiencing Manic Episodes of Bipolar Affective Disorder
    • Uncontrolled Epilepsy
    • Anyone Taking Thioridazine or Pimozide
    • Anyone Allergic to Ingredients of Paroxetine

    Paroxetine is contraindicated for the following:

    Anyone who has taken any of the following drugs within the last 2 weeks:

    • Rasagiline
    • Tranylcypromine
    • Isocarboxazid
    • Phenelzine
    • Selegiline

    Paroxetine is contraindicated for the following:

    Anyone who has taken any of the following drugs within the last few days:

    • Moclobemide
    • Linezolid
    • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

      Clair C. | West Hollywood, CA