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Nortriptyline is a custom pharmacy drug that is classified in the family of drugs known as tricyclic antidepressants. Nortriptyline works to balance certain chemicals within the brain (neurotransmitters) and may help to stabilize mood in patients suffering from mental health issues such as depression. Tricyclic antidepressants are sometimes prescribed for patients exhibiting symptoms of depression or anxiety.


Nortriptyline is taken orally, in most patients, one to four times a day or as prescribed by your physician. Consult with your compounding pharmacist if you have further questions once you begin treatment. Always follow your physician's exact instructions and directions on usage and dosage. As is true with many modern medicines, nortriptyline can be compounded into various forms of delivery; ask your doctor what might be best for you. If you are prescribed a liquid form of nortriptyline, take care to measure the medicine with an approved measuring device. Never use a common teaspoon or tablespoon, as this will most likely create a situation where your doses will be too small or too large, either of which can be potentially harmful.


Side effects are always a possibility anytime a new drug is introduced into the body. Ask your physician to discuss all possible side effects with you so you will be prepared and know what to watch for. If you experience anything that persists or seems to be getting worse, see your doctor right away. For your information, a partial list of some potential side effects is provided below.

  • Dry Mouth
  • Blurred Vision
  • Weight Gain
  • Dizziness
  • Constipation
  • Difficulty Urinating
  • Drowsy Feeling

Severe Side Effects:

Unfortunately some patients may experience more severe side effects. Severe side effects always require prompt medical attention so if you find that you are experiencing anything that feels severe or perhaps anything on the list provided below, see your doctor right away or go to a quality medical care center or emergency care facility for treatment immediately. Some of the known severe side effects are listed below. Please note this list is only a partial list and you may experience severe side effects that are unique to you, or not listed herein.

  • Shaking
  • Muscle Spasms
  • Diarrhea
  • Accelerated Heartbeat
  • Loss of Coordination
  • Hallucinations
  • Vomiting
  • Nausea
  • Twitching
  • Abnormal Agitation
  • Severe Dizziness
  • Extreme Restlessness
  • Persistent Heartburn
  • Odd Facial Expressions
  • Severe Stomach Pain
  • Enlarged Breasts
  • Painful Breasts
  • Decreased Libido
  • Decreased Sexual Ability
  • Fainting
  • Eye Pain
  • Swelling in Eye
  • Widened Pupils
  • Vision Changes
  • Seizures
  • Rash
  • Swelling (tongue, throat, face)
  • Difficulty Breathing


Never take this drug unless your physician has screened you and he or she has deemed it necessary, and safe, for your treatment.

There are many possible contraindications for the use of this drug. Ask your physician to explain them and be sure that nortriptyline is safe for your use.

Nortriptyline is contraindicated for anyone with the following:

  • Hypersensitivity to Tricyclic Antidepressants
  • Current Users of MAOIs
  • Recent Users of MAOIs (within the past 30 days)
  • Recent Myocardial Infarction

WARNING: Do not use MAOIs within 30 days after stopping the use of nortriptyline.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA