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Norethindrone is a custom pharmacy drug classified in the family of drugs known as progestins. Specifically, norethindrone is a form of the female hormone progesterone. Norethindrone has a myriad of uses in medicine and is often given as a contraceptive for prevention of pregnancy, and to treat endometriosis, menstrual disorders, and abnormal hormonal imbalance related vaginal bleeding. Norethindrone is effective as it disables the production of certain hormones within the uterus.


Norethindrone may come in various forms but is commonly given as an oral tablet. Dosage and usage is entirely predicated upon the specific medical condition, age, and/or health status of each individual patient. Consult with your doctor for more information about this drug and how to use it safely and effectively during your treatment.


Side effects can occur with any drug. Anyone using norethindrone may experience some unwanted side effects. While side effects may present then pass quickly in some cases, always see your doctor right away if any side effect worsens or lingers. Some of the more commonly seen and experienced side effects are listed below.

  • Enlarged Breasts
  • Tender Breasts
  • Difficulty Falling Asleep
  • Trouble Staying Asleep
  • Acne
  • Growth of Hair on Face
  • Irregular Vaginal Bleeding
  • Spotting
  • Menstrual Flow Changes or Irregularities
  • Upset Stomach
  • Weight Change

Severe Side Effects:

While many patients and users of this drug will experience few or no side effects, others may perhaps experience severe side effects that require medical treatment quickly. If you experience anything that feels severe or anything on the list below, see your doctor right away or go to a medical treatment facility for treatment at once.

  • Dizziness or Faintness
  • Numbness (arm or leg)
  • Swelling (hands, arms, feet, ankles, lower legs)
  • Jaundice
  • Difficulty Breathing
  • Trouble Swallowing
  • Depression
  • Mood Shifts or Mood Swings
  • Brown Patches (on face)
  • Skipped Periods
  • Severe Pain in Abdomen
  • Hives and/or Rash
  • Itching
  • Loss of Vision
  • Blurred Vision
  • Double Vision
  • Bulging Eyes
  • Migraine Headache
  • Pain or Warmth (back of the lower leg)
  • Sudden Sharp Chest Pain
  • Crushing Chest Pain
  • Heaviness in Chest
  • Short of Breath
  • Coughing up Blood
  • Difficulty with Speech
  • Slow Speech


Talk to your doctor about all possible contraindications and do not take norethindrone if it is contraindicated for any reason due to your age, current health status, medical condition, or other. Only your doctor can decide if norethindrone is safe for use. Never take norethindrone without the expressed permission from your primary care doctor.

Norethindrone is contraindicated for all of the following conditions:

  • Undiagnosed Vaginal Bleeding
  • Pregnancy
  • Current, or History of Breast Cancer
  • Impaired Liver Function
  • Deep Vein Thrombosis
  • Current, or History of Pulmonary Embolism
  • Liver Disease
  • As Diagnostic Test for Pregnancy
  • Hypersensitivity to Components of Norethindrone
  • Active Arterial Thromboembolic Disease
  • Arterial Thromboembolic Disease (within the last year)
  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA