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Mupirocin is a custom pharmacy drug classified as an antibiotic. Mupirocin is used to treat various skin infections and works by stopping bacteria growth. This drug is commonly used to combat staphylococcus aureus, streptococcus pyogenes, and other bacteria that cause infections such as impetigo, etc.


Mupirocin is generally administered as a topical medication, often as an ointment. Usage is typically up to three times daily for one, possibly two weeks if needed, or as directed by your physician. Always wash and gently dry the target area before application, then apply only a small amount, just enough to cover the area with a thin layer. Never allow this medication to get into the eyes, mouth, or nose.


Side effects can sometimes occur with the use of mupirocin. Talk to your doctor about possible side effects before beginning use of this drug. Watch for side effects and see your doctor if you experience any that are worsening or hanging around. Common side effects seen with mupirocin are:

  • Rash
  • Pain
  • Itching
  • Burning
  • Stinging

Severe Side Effects:

While less common, severe side effects are possible. See your doctor right away if you experience anything that feels severe, or any of the known severe side effects listed below.

  • Unrelenting Diarrhea
  • Blood or Mucus in Stool
  • Stomach Cramps
  • Stomach Pain

Severe allergic reactions can occur with almost any medication. Watch for signs of potentially severe allergic reactions and seek medical attention immediately if you experience any of the following:

  • Itching and/or Swelling (face, throat and tongue)
  • Severe Dizziness
  • Rash
  • Trouble Breathing


Never take this drug unless cleared to do so by your primary care physician. Mupirocin is a strong antibiotic and only your physician should decide if it is appropriate for your treatment.

Ask your physician to provide you with a complete overview of possible contraindications and risks associated with the use of mupirocin.

Mupirocin is contraindicated for anyone with any of the following:

  • Allergy (to mupirocin or its ingredients)
  • Skin Irritation Issues
  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA