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Methylcellulose is a custom pharmacy drug, a bulk-forming laxative designed to allow stools to become more watery and softer allowing for easier bowel movements. Methylcellulose is predominantly used for constipation and to maintain bowel regularity.


Methylcellulose is generally taken one to three times daily as directed by your doctor. If taking the powder form, it should be mixed with at least eight ounces of water. Be sure to drink another full glass of water directly after taking the water/powder mixture to hydrate yourself and ensure the medicine is fully digested.


Side effects may be encountered with the use of methylcellulose. See your doctor right away if any side effect lingers or gets worse. Some of the most commonly experienced side effects are listed below.

  • Gas
  • Cramps
  • Stomach Pain

Severe Side Effects:

This drug may cause severe side effects in some patients or users. Do not underestimate the possible danger of a severe side effect. While it is rare, some patients or users of methylcellulose may experience side effects that are deadly. If you experience anything that feels severe, or anything on the list below, get emergency medical help immediately.

Allergic Reaction Signs:

  • Itching
  • Hives
  • Rash
  • Trouble Breathing
  • Trouble Talking
  • Unusual Hoarseness
  • Wheezing
  • Tightness in Chest
  • Tightness in Throat
  • Swollen, Peeling, or Blistering Skin (with or without fever)
  • Swelling (mouth, lips, tongue, face, or throat)

Other Severe Side Effects:

  • Diarrhea or Extremely Loose Stools
  • Extreme Stomach Pain
  • Chest Pain
  • Vomiting

NOTE: As the difference between a mild side effect classification and a severe side effect classification may sometimes be only the level of severity, never take a risk. If you experience anything that feels severe or is troubling or concerning, get medical treatment right away.


Ask your doctor to discuss all possible contraindications that may be relevant to your condition, age, or health status.

All patients, especially anyone with any of the conditions listed below, should not take or use this drug unless cleared by their doctor for use.

  • Trouble Swallowing
  • Stomach Pain with Nausea and/or Vomiting
  • Irritable Bowel Syndrome
  • Blockage of Esophagus
  • Constipation Lasting for a Week or Longer
  • Sudden Changes in Bowel Habits
  • Stomach Blockage
  • Rupture in Stomach Wall or Intestinal Wall
  • Appendicitis
  • Allergy to Methylcellulose Analogues

Do not use methylcellulose if you are pregnant or breastfeeding, planning a pregnancy, or about to begin breastfeeding.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA