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Melatonin is a naturally occurring hormone found in the human body. It is synthetically manufactured for use as a pharmacy drug and over-the-counter supplement. Within the body, melatonin is the body's biological clock, as it has dominion over the sleep/wake cycle internally. Our bodies produce more melatonin during the darker days of winter months, and less during the long days of summer. Melatonin supplements work similar to natural hormones and help induce sleep. Treating insomnia caused by various diseases and conditions is one of melatonin's obvious uses, but it is also used to treat Alzheimer's disease, bipolar disorder, endometriosis, depression, COPD, liver disease, postural tachycardia syndrome, osteoporosis, jaw pain, urinary problems, jet lag, and other issues. Ask your doctor about melatonin's many uses.


Melatonin may be compounded for you in various forms such as capsules, sublinguals, tablets, liquids, solutions, and more. Talk to your compounding pharmacist if your doctor has prescribed melatonin for your treatment. Many people take melatonin orally. Your doctor will prescribe a proper dosage for your treatment plan. Follow his or her directions on usage and dosage.


Side effects could occur while taking melatonin. Talk to your doctor about the possible side effects you could encounter. While many tolerate this drug reasonably well, others may experience side effects. If you are taking melatonin and experience any side effects that linger or seem to be getting worse, see your doctor promptly. Common side effects seen with melatonin are:

  • Depression
  • Irritability
  • Headaches
  • Drowsiness (daytime)
  • Dizziness


Do not take melatonin until you have discussed your intentions with your primary care doctor and he or she has given you the go-ahead to use it.

Melatonin may be contraindicated for a host of reasons from disease contraindications, drug interaction problems, medical conditions or issues, etc. Check with your doctor and have a frank discussion about the contraindications that may be relevant to you and your health status or condition.

Melatonin is contraindicated for:

  • Concurrent Immunosuppressive Treatment
  • Pregnancy
  • Breastfeeding

Caution is recommended for the conditions listed below. Do not take melatonin if you suffer from anything listed below.

  • Hypertension
  • Seizure Disorder
  • Depression
  • Impaired Liver Function
  • Liver Problems

Melatonin may be inadvisable for anyone under the age of 20 years. Ask your doctor for more information.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA