Melanotan II (formula C50H69N15O9) is a manufactured analogue of the peptide hormone classified as α-melanocyte-stimulating hormone, which is produced naturally in the pituitary gland. Melanotan II operates as a non-selective agonist of the following melanocortin receptors: MC1, MC3, MC4, and MC5. Activation of the MC1 receptor may stimulate melanogenesis, the process by which melanocytes produce melanin for the eyes, skin, and hair.
Typically administered as an injection, melanotan II may be given for erectile dysfunction—stimulating erections via brain activity—and for the prevention of skin cancers, and sometimes for actual tanning of the skin. Melanotan II may produce some unwanted side effects such as nausea, vomiting, flushing, loss of appetite, and possibly the feeling of a need to stretch or yawn.
Typical dosing for melanotan II is via vials, often in powder form that should be refrigerated when not in direct use. Reconstitution is achieved by adding specific amounts of bacteriostatic water. A doctor's decision regarding a particular patient's dosage will be predicated upon the patient's current health status, medical history, and age, as well as other medical indicators and current medical conditions. Some research has indicated that negative side effects such as nausea may be reduced or eliminated if injections are administered after dinner or before bedtime.
Individual patients could experience varying results that may be dependent upon select variables such as sun exposure, use of tanning beds, natural color, body size, and general reaction to the hormone.
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