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List of Medications

Isosorbide Dinitrate

Isosorbide dinitrate is classified in the family of drugs known as nitrates. It is a vasodilator and as such it expands arteries and veins within the body and allows for more ease of blood flow. This expansion lowers the pressure in the arteries and allows the heart to do its pumping work with less strain. Isosorbide dinitrate is commonly given to relieve chest pain.


Isosorbide dinitrate is often administered as a tablet that can be taken with or without food. Sublingual tablets are designed to be dissolved underneath the tongue. Never chew, crush, or bite into tablets. Your physician may feel that another form of delivery would be easier or more effective, if so, your compounding pharmacist can talk to your physician and then craft a method of delivery for the medication that is most suited to your needs, tailored to your condition. Isosorbide dinitrate can be compounded into solutions for injection, tablets, capsules, and suspensions.


Isosorbide dinitrate may cause some unwanted side effects. Common side effects seen with the use of isosorbide dinitrate are:

  • Headaches
  • Drop in Blood Pressure (when standing up from a previous position of sitting)
  • Dizziness
  • Flushing
  • Palpitations
  • Feeling Weak

If you experience any side effect that is persisting or getting worse, contact your physician. If you experience anything that is troubling or feels severe, seek medical attention immediately. Never delay seeking medical help at once if any side effect is concerning to you.


All patients, especially anyone with a history of heart problems/issues, who is considering the use of isosorbide dinitrate should consult with their physician before beginning use.

There is insufficient data on the use of isosorbide dinitrate by pregnant or breastfeeding women so this drug should not be taken by anyone who is either.

Isosorbide dinitrate may be contraindicated for many diseases and conditions. Check with your physician and ask if there are any contraindications specific to you.

Isosorbide dinitrate may be contraindicated for the conditions listed below. Ask your doctor if these apply to you.

  • Severe Anemia
  • High Pressure in Skull
  • Hypertrophic Cardiomyopathy
  • Heart Attack
  • Hemorrhage in Brain
  • Unusually Low Blood Pressure
  • Methemoglobinemia
  • Malabsorption

Do not take isosorbide dinitrate if you have an allergy to nitrate analogues.

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    Clair C. | West Hollywood, CA