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Hydrocortisone is a complex custom-made pharmacy drug that is classified alongside other potent drugs in the family of drugs known as corticosteroids. Hydrocortisone works by triggering the skin's own inherent organic matter to 'go to work' in the relief of itching, redness, and swelling that can develop from a number of common skin conditions.


Hydrocortisone is a topical agent that is most often delivered as a cream, liquid solution, ointment, lotion, or spray—all for external use on the skin. Your doctor may prescribe its use for one to four times per day; follow your doctor's directions. Hydrocortisone should be applied in a consistent manner and on a consistent schedule, so whatever time of day you apply it, stick to that schedule regularly per day for the course of your use of hydrocortisone as per your doctor's instructions. Never bandage or wrap the treatment area unless your doctor gives you specific instructions to do so.


Side effects may present while using hydrocortisone. With the use of hydrocortisone, as with all drugs, watch for side effects and report them to your doctor right away if they are intensifying or lasting/lingering. For your convenience please find a partial list of a few of the side effects that could be experienced by anyone using this drug. Ask your compounding pharmacist and doctor about what to expect during your course.

Possible Common Side Effects:

  • Unwanted Hair Growth
  • Red Bumps/Rash (around mouth)
  • Small White and/or Red Bumps (on skin)
  • Itching Skin
  • Burning Skin
  • Irritation of Skin
  • Dryness of Skin
  • Redness of Skin
  • Acne
  • Changes in Skin Color

Severe Side Effects:

If you experience any side effect that feels severe to you, get immediate medical treatment. A partial list of a few severe side effects that are possible is provided below:

  • Swelling, Redness, Or Possible Signs of Skin Infection in Area of Application
  • Severe Rash


Some patients should not use hydrocortisone. Before using this drug you should talk to your doctor to find out if it is safe for your use.


Hydrocortisone may be contraindicated in the cases of pregnancy, breastfeeding, or pediatrics. If any of these apply to you or someone you are caring for, do not use hydrocortisone until being cleared to do so by a doctor who has full knowledge of the medical history and condition, including current and recent drug usage, of the intended user of hydrocortisone.

Other medical conditions, diseases, and drug interactions may make the use of hydrocortisone inadvisable for select patients. Discuss your options and medical condition with your doctor before using hydrocortisone.

Hydrocortisone is contraindicated for anyone with a sensitivity or allergy to hydrocortisone or any of its ingredients.

Hydrocortisone may be contraindicated for anyone with a sensitivity or allergy to corticosteroids in general. Ask your doctor if this applies to you.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA