Call us
List of Medications

HCG (Human Chorionic Gonadotropin)

HCG (Human Chorionic Gonadotropin) is a natural hormone that is produced during pregnancy by the placenta after a fertilized egg begins adhering to the uterus wall. An assortment of pregnancy tests use the presence of HCG as the defining measurement to determine a pregnancy positive result. HCG has multiple tasks in the body. In men, HCG is utilized as a means to boost sperm count. In women, it is used to trigger ovulation. Occasionally HCG is used in boys who have a certain pituitary gland disorder. Physicians may prescribe HCG for other issues, but fertility issues are by far the most dominant use of this hormone. HCG can be created through recombinant DNA/genetic modification procedures or prepared from urine derived from pregnant women.


HCG is typically given as an intradermal or intramuscular injection. Some patients receive injections at their doctor's office; however, HCG can be compounded by your compounding pharmacist for your use at home if you prefer. If you think at home injections would be preferable, ask your doctor for instruction on how to properly perform injections and dispose of needles. If you have not mastered the technique of injection then you should not inject yourself. Once you have mastered the technique and fully understand how to perform injections, use injection needles only once, then dispose of them properly in a puncture proof container. Consult with your doctor on the pros and cons of prefilled syringes versus power/liquid mixtures. Your compounding pharmacist can assist you with questions on where to procure an approved needle disposing container and how to properly dispose of them, how to store syringes and ingredients, and any other topic you in which you may need further information or clarification.


Hormones are powerful and as such anyone beginning any hormone therapy or injections may have an adjustment period. Side effects are possible with any drug, medication, hormone, etc. that is introduced into the body. Some may experience no side effects, still others may experience one or two or several. Everyone's body reacts uniquely to medication and drugs so your experience may be typical or atypical. Notice any changes and if you feel that you are experiencing a side effect, observe then contact your doctor if it is worsening or lingering/persisting. A list of some of the more commonly seen/experienced side effects is below:

  • Swelling
  • Water Weight Gain
  • Breast Tenderness
  • Breast Swelling
  • Restlessness
  • Irritability
  • Headache
  • Depression

At Site of Injection:

  • Swelling
  • Pain
  • Irritation

Severe Side Effects:

Some may experience more severe side effects that require medical treatment immediately. Watch for any severe side effects and seek immediate medical assistance if you experience anything that is severe or troubling.

Watch for signs of a severe allergic reaction. Severe allergic reactions are serious and require medical attention. Some possible signs of a severe allergic reaction are:

  • Difficulty Breathing
  • Hives
  • Swelling (face, tongue, throat, lips)

If you experience any signs of a severe allergic reaction, or any side effect that you are concerned may be an allergic reaction, get medical help immediately.

If you experience any signs of a blood clot such as warmness, redness, pain, tingling in your arms or legs, numbness, confusion, intense headaches, or dizziness, speak to your doctor right away.


Use of HCG may instigate, in some women, ovarian hyperstimulation syndrome (OHSS). OHSS could be dangerous, even life-threatening. If you experience ANY symptoms of OHSS, get emergency medical assistance immediately. Some of the possible symptoms of OHSS are as follows:

  • Diarrhea
  • Urinating Less than Normal or Infrequently
  • Swelling (hands or legs)
  • Stomach Pain and/or Swelling
  • Weight Gain
  • Extreme Pelvic Pain
  • Nausea and/or Vomiting
  • Shortness Of Breath

IMPORTANT NOTE: As there may be some overlap with side effects being listed as 'common' or 'severe' and the only way to tell if it warrants immediate medical attention and treatment is by the severity, always err on the side of caution and get emergency medical treatment immediately if you have any concern whatsoever.


All patients considering the use of HCG should consult with their doctor before using.

There may be many diseases, drug interactions, medical conditions, and more that could make the use of HCG inadvisable for some patients. Consult with your doctor on all the possible contraindications.

HCG is contraindicated for anyone with any of the following:

  • Androgen-Dependent Neoplasia
  • Precocious Puberty
  • Prostatic Carcinoma
  • Known Allergic Reaction to Chorionic Gonadotropin

Do not use HCG if you are pregnant or planning a pregnancy, breastfeeding, or about to begin breastfeeding.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA