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Fluocinonide is a powerful corticosteroid, a custom pharmacy drug. As a topical corticosteroid, this medication is useful when treating swelling, dryness, redness, crusting, scaling, itching, and other symptoms that come with skin conditions such as eczema, atopic dermatitis, allergies, psoriasis, and rash. Fluocinonide is sold as a brand name drug as well as a generic and has been effective with some patients suffering from these distressing symptoms of skin disorders.


Fluocinonide is usually given as a topical cream, gel, solution, or ointment and as such is to be applied only to skin. However, fluocinonide should not be applied to the face, underarms, or groin unless specifically cleared to do so by your physician or healthcare provider. Always wash the application area before applying fluocinonide topical. After washing and gently drying the area of intended application, apply a very small amount of fluocinonide, just enough to thinly cover the area, and gently rub it in. Do not dress or bandage the area after applying fluocinonide unless your physician specifically directs you to do so. Apply 2 to 4 times daily or as directed by your physician. For diaper area application on infants, after application do not use restricting or tight diapers to avoid chafing or disturbance of the treatment area.

IMPORTANT NOTE: Always wash hands very well after use!


Some patients have experienced side effects. Observe your body and especially the affected area for any side effects during your course of treatment. Some of the more common side effects encountered with fluocinolone are:

  • Headache
  • Acne
  • Burning Skin
  • Itching Skin
  • Dry Skin
  • Change of Color of Skin
  • Cracking of the Skin

If you experience any of the above side effects or perhaps any other side effects that are concerning to you, persisting, or getting worse, contact your doctor right away.

Severe Side Effects:

While some patients may tolerate fluocinonide well, other patients may possibly encounter some severe side effects. Be alert and notice any sign of severe side effects and seek medical assistance immediately if you experience:

  • Skin Rash (severe)
  • Skin Infection (oozing pus, redness, swelling, etc.)
  • Trouble Breathing
  • Wheezing
  • Fainting
  • Weight Loss
  • Difficulty Swallowing
  • Depression
  • Vomiting
  • Slow Wound Healing
  • Additional Growth of Body Hair
  • Cushing's Syndrome (ask your doctor for details; a partial listing of symptoms due to Cushing's syndrome are listed above as part of this list)

If you encounter side effects that are severe in nature, or if you are unsure, it is always best to get medical treatment immediately. Never delay seeking out medical treatment, as severe side effects are potentially dangerous.


The use of fluocinolone may not be advisable for some patients. Check with your doctor for a consultation on possible contraindications.

Fluocinolone is contraindicated for patients and users allergic to corticosteroids or any of the ingredients of corticosteroids.

Do not use cosmetics near or on the treated area.

WARNING: Take extra care to avoid getting any fluocinonide in your nose, mouth, or eyes. Accidental insertion of fluocinonide into the eyes may exacerbate glaucoma or generate the disease.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA