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Ergotamine is classified as an ergot derivative and is primarily used in the treatment of severe migraine headaches. Migraine headaches may present with aura (visual symptoms described as dark spots, flashing lights, or undulating lines) or without.


Ergotamine may be compounded into a delivery method tailored for your condition, though it is often delivered in tablet form. Tablets should be placed under the tongue and given proper time to dissolve. Never crush, swallow, or chew ergotamine tablets. Do not take more than 3 ergotamine tablets in any 24-hour period. Ergotamine is not intended for daily use; consult with your physician about other drug options if you are having daily migraines. Consult with your compounding pharmacist or physician if you have questions while taking this drug.

NOTE: Do not eat grapefruit or drink grapefruit juice while using ergotamine unless your physician has specifically cleared this.


Some users may experience no side effects, though others may experience one or more side effects. Until beginning use, it is impossible to predict exactly how the drug will affect you regarding possible side effects. Common side effects seen with ergotamine are as follows:

  • Vomiting
  • Nausea
  • Dizziness

Other side effects are possible. Contact your physician if you are enduring any side effects that seem to be persisting or are worsening over time.

Severe Side Effects:

  • Weakness in Arms or Legs
  • Unusual Swelling and/or Weakness.
  • Persistent Headache
  • Fast Heartbeat
  • Irregular Heartbeat
  • Slow Heartbeat
  • Chest Pain
  • Shortness of Breath
  • Muscle Pain
  • Cold, Pale, or Tingling Hands and/or Feet
  • Blue Hands or Feet
  • Severe Dizziness
  • Persistent Dizziness

Watch for possible allergic reaction to ergotamine and get medical help immediately if you experience ANY allergic reaction.

Possible Signs of Allergic Reaction to Ergotamine:

  • Swelling of the Face, Mouth, Tongue or Lips
  • Itching
  • Rash or Hives
  • Tightness in the Chest
  • Difficulty Breathing


Ergotamine is strictly contraindicated for pregnancy and breastfeeding. Ergotamine may harm a fetus or nursing baby. Do NOT use if pregnant or breastfeeding, planning a pregnancy or about to begin breastfeeding.

Ergotamine is for adults only. Do not give this drug to children.

Exercise caution and consult with your physician before using if you are elderly.

Do not use ergotamine if you have blood pressure or blood vessel problems.

Do not use if you have decreased kidney or liver functions.

Do not use if you have any severe infections.

Check with your physician for a comprehensive list of all possible contraindications that may be relevant to your medical condition, age, health status or other.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA