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Doxepin can be compounded by your compounding pharmacist in many forms for administration. Oral liquid and capsule forms are popular and if prescribed your doctor or pharmacist will provide you will information on dosage and usage. The capsules can be taken with or without food. The oral liquid is a concentrate that is designed for dilution into a beverage such as water, orange juice, or other juice. Do not dilute the concentrate into carbonated beverages.


Users of doxepin have experienced side effects so you should be aware of any changes you feel within or on your body. If you experience any side effects that are concerning, or any side effects that are not going away (persisting) or are exacerbating, seek medical assistance. A partial list of some commonly seen side effects is as follows:

  • Dry Mouth
  • Mouth Sores
  • Vomiting and/or Nausea
  • Dizziness
  • Increase in Size of Pupils
  • Headache
  • Hair Loss
  • Increased Breast Size
  • Constipation
  • Changes in Appetite
  • Weight Change
  • Changes in Taste
  • Skin Becoming More Sensitive to Sun
  • Flushing
  • Difficulty Urinating
  • Excessive Urination
  • Excessive Thirst
  • Ringing in Ears
  • Milky Discharge from Nipples (Females)
  • Indigestion
  • Diarrhea
  • Changes in Sex Drive
  • Swollen Testicles
  • Excessive Sweating
  • Chills
  • Weakness / Tiredness

Severe Side Effects:

If you experience any of the following severe side effects seek medical treatment immediately:

  • Skin Rash
  • Itching
  • Swelling
  • Rapid Heartbeat
  • Yellow Skin or Eyes
  • Unusual Bleeding
  • Abnormal Bruising

IMPORTANT NOTE: Some users of antidepressants, often younger users up to their mid 20s, became suicidal or experienced suicidal thoughts in varying degrees during clinical trials. If ANY suicidal thoughts are experienced do not delay, get medical assistance immediately.


There are many diseases, conditions, and drug interactions which could make the use of doxepin inadvisable. Check with your doctor for a full list of contraindications before using doxepin.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA