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Clorpheniramine is an antihistamine that is prescribed to treat many allergies, hay fever, as well as the common cold. Clorpheniramine works to combat the irritating symptoms that come with those conditions such as itchy eyes that may also be watery or red, sneezing, runny nose, and itchy nose or throat.

How to Use Clorpheniramine

Clorpheniramine comes in multiple forms customized for specific patient needs such as tablets and capsules, extended-release tablets and capsules, chewable tablets, and a liquid solution, all of which are taken orally. This drug may be a standalone drug or a primary ingredient of another medication. Ask your doctor about your options.

Possible Side Effects

Many and various side effects are possible when taking clorpheniramine. While many patients may feel few or no side effects, watch for any changes in your body and if you experience side effects that are troubling or lingering, or getting worse, contact your doctor. A partial list of some commonly seen side effects is below:

  • Nausea
  • Vomiting
  • Loss of Appetite
  • Drowsiness
  • Dry Mouth, Nose, and Throat
  • Increased Chest Congestion
  • Constipation
  • Headache

Severe Side Effects:

If you experience any side effects that you feel are concerning, including any of the following severe side effects, seek medical treatment immediately:

  • Vision Problems
  • Difficult Urination


Clorpheniramine may be contraindicated for patients who have certain medical conditions listed below. Check with your doctor before beginning use of clorpheniramine if you suffer from any of the following:

  • Stomach or Intestine Blockage
  • Chronic Difficulty with Bowel Movements
  • Overactive Thyroid Gland
  • High Blood Pressure
  • Closed Angle Glaucoma
  • Stenosing Peptic Ulcer
  • Blockage of Urinary Bladder
  • Enlarged Prostate
  • Cannot Empty Bladder
  • Chronic Obstructive Lung Disease

Clorpheniramine is contraindicated for patients who are allergic to the following:

Antihistamines, Antihistamines – Alkylamine

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    Clair C. | West Hollywood, CA