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Clomiphene is a custom drug classified as an ovulatory stimulant. This drug is sometimes prescribed for women seeking to become pregnant and is used to trigger egg production (ovulation) when their bodies are not naturally producing eggs.

How to Use Clomiphene

Clomiphene is taken orally, typically for 5 days at regular intervals starting on the 5th day of a woman's menstrual cycle. It is important to follow your physician's specific direction while taking this drug and to have your physician monitor your condition regularly throughout the short course.

Possible Side Effects

Some patients may experience side effects. Be aware of any of the common side effects that occur and seek treatment if they seem to be hanging on or becoming more severe. Common side effects seen with clomiphene are:

  • Upset Stomach and/or Vomiting
  • Feeling Warm (flushed)
  • Discomfort in the Breast
  • Abnormal Vaginal Bleeding
  • Headaches

Severe Side Effects: If you observe any of the following severe side effects get medical treatment immediately and call your physician:

  • Visual Spots / Flashes
  • Blurry Vision
  • Double Vision
  • Weight Gain
  • Shortness of Breath
  • Stomach Swelling
  • Stomach Pain
  • Lower Stomach Pain


Clomiphene may be contraindicated for anyone with any of the following diseases, conditions, or symptoms:

  • Tumor in the Pituitary Gland
  • Cancer in the Uterus Lining
  • Decreased Level of Thyroid Hormones (Untreated)
  • Disease of Ovaries with Cysts
  • Thyrotoxicosis
  • Liver Problems
  • Depression
  • Eyesight Problems
  • Seeing Spots
  • Blind Spot (eye)
  • Obstruction of a Blood Vessel by Blood Clot
  • Blood Clot in Vein
  • Intracranial Lesion
  • Extremely Decreased Function of the Cortex of Adrenal Gland
  • Endometriosis
  • Ovarian Enlargement due to Infertility Treatment
  • Ovarian Cyst
  • Pregnancy

Talk to your physician before taking clomiphene if you have any of the diseases, conditions, or symptoms listed above, or other conditions that you feel are important to note.

WARNING: If you are prescribed clomiphene and begin taking it, you should not use it for more than 6 menstrual cycles as clomiphene increases the risk for ovarian cancer. Discuss the risks of clomiphene with your physician before beginning use.

Clomiphene may interact with other drugs. Be sure to tell your physician about all the drugs you are currently taking if you are considering clomiphene.

WARNING: Do not take clomiphene if you are pregnant or planning a pregnancy. Clomiphene usage increases fetal risks.

CAUTION: It is unknown as to whether clomiphene excretes into human milk. If you are breastfeeding or planning to breastfeed do not take clomiphene without first undergoing a full medical consultation with your physician about all your ovulatory stimulant options.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA