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Cevimeline is a custom drug classified in the drug family known as cholinergic agonists, prescribed to combat dry mouth brought on by the immune disease known as Sjogren's syndrome. Cevimeline has been shown to stimulate nerves that impact the body's saliva production thus enabling patients to swallow and speak with greater ease and comfort.

How to Use Cevimeline

Cevimeline is taken orally, typically 3 times a day as prescribed by your physician. It can be taken with or without food. Patients taking cevimeline should follow a tight dosing schedule as it is important for the drug to be received by the body at regular and consistent intervals for the duration of the prescribed course. Many patients have seen improvement of their conditions within one to two weeks after beginning treatment with cevimeline. Patient results may vary. Consult with your physician or compounding pharmacist for specific questions after being prescribed cevimeline.

Possible Side Effects

There can be side effects with almost any drug so it is important to watch for side effects as you begin your course of cevimeline. Common side effects seen with cevimeline are:

  • Rhinitis
  • Nausea
  • Diaphoresis

If you experience rhinitis, nausea, or diaphoresis, or other side effects, seek medical assistance if you feel it is warranted. If any side effects are increasing in intensity or seem to be lingering, seek medical treatment.

Severe Side Effects

Some patients have experienced more severe side effects. While some minor side effects can also be or become severe side effects, it is always best to seek medical treatment whenever you feel it is warranted. Check the list below and seek emergency medical help if you experience any of these potentially severe side effects:

  • Change in Vision
  • Excessive Sweating
  • Severe Headache
  • Tearing in Eyes
  • Abdominal Cramps
  • Changes in Heartbeat
  • Difficulty with Breathing
  • Uncontrollable Shaking Hands
  • Confusion
  • Change in Blood Pressure


All patients considering the use of cevimeline should first consult with their physician before beginning use as there are many medical conditions that could be affected by the use of cevimeline. It is important for your physician to know your medical history and be aware of any medications that you are currently using.

Do not use cevimeline if you are pregnant, about to become pregnant, breast-feeding or considering breast-feeding unless you have consulted with your physician beforehand and they have decided the use of cevimeline is necessary.

  • "It is rare to find health professionals who are so willing to educate the patient on what they need to know."

    Clair C. | West Hollywood, CA