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Aztreonam is a carbapenem antibiotic that kills bacteria. Aztreonam is prescribed in cases of infection as it works to destroy bacteria that cause infections within the body such as those originating in the urinary tract, blood, abdominal area, skin, and respiratory tract. Aztreonam is also often used as an agent to help prevent infection before, during, and then after a surgical procedure.

How to Use Aztreonam

Aztreonam is most often in a powder form that is then mixed with a liquid and is typically administered as an injectable, intravenously or intramuscularly. Patients should consult with their prescribing physician regarding treatment, dosage, proper administering, and schedule.

Possible Side Effects

Aztreonam may cause side effects. The most common side effect is fever. Contact your physician right away if you develop a fever that persists.

Other Common Side Effects:

  • Stomach Pain
  • Stuffy Nose
  • Sore or Aching Throat
  • Vomiting
  • Rash

If you experience side effects, listed above or otherwise, that persist or that you feel are worsening, consult with your physician.

Serious Side Effects:

There are many serious side effects that could be experienced with the use of aztreonam. If you experience any serious side effects seek medical attention. A partial list of some of the known serious side effects includes:

  • Cough
  • Trouble Breathing
  • Fever
  • Chest Discomfort or Tightness
  • Shortness of Breath
  • Noisy Breathing


Anyone considering beginning a new medication is advised to first consult with their physician to discuss all their medications, medical history, and options. You should not take aztreonam if you have liver problems or a history of liver issues, disease, or problems. You should not take aztreonam if you have kidney disease or a history of kidney disease or kidney problems. You should not take aztreonam if you have or have had clostridium difficile infection. Do not take aztreonam if you are pregnant, planning a pregnancy, or currently breast-feeding or planning to breast feed unless you first consult with your physician and are given their approval for the use of aztreonam.

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